Quarterly report pursuant to Section 13 or 15(d)

Stockholders Equity (Details)

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Stockholders Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Jun. 26, 2022
Jun. 26, 2022
Mar. 29, 2022
Dec. 31, 2021
Oct. 31, 2021
Dec. 31, 2020
Jun. 30, 2022
Jun. 30, 2022
Jul. 28, 2022
Nov. 30, 2017
Stockholders Equity (Details) [Line Items]                    
Market sales agreement, description           pursuant to a registration statement on Form S-3 declared effective by the Securities and Exchange Commission on December 11, 2020, the Company entered into an Open Market Sales Agreement (“ATM Agreement”) with Jefferies LLC. (“Jefferies”), which provides that, upon the terms and subject to the conditions and limitations in the ATM Agreement, the Company may elect, from time to time, to offer and sell shares of Common Stock with an aggregate offering price of up to $50,000, with Jefferies acting as sales agent. During the six months ended June 30, 2022, the Company sold 27,171 shares of Common Stock under the ATM Agreement, at an average price of $1.36 per share, raising aggregate net proceeds of approximately $37, after deducting an aggregate commission of $1.        
Common stock per share                 $ 1.2  
Contract liability         $ 1,976          
Preferred stock, shares authorized       1,000,000     1,000,000 1,000,000    
Preferred stock, par value       $ 0.0001     $ 0.0001 $ 0.0001    
Fair value at the grant date             $ 1,307 $ 1,477    
Shares of issued warrants                   2,974
Warrants, description               The warrants were fully vested at their grant date and will expire immediately prior to a consummation of an M&A transaction.    
Stock Options [Member]                    
Stockholders Equity (Details) [Line Items]                    
Employees consideration, description   On June 26, 2022, the Board of Directors approved the grant of 350,500 options to 53 employees, and one consultant under the Company’s 2019 Equity Incentive Plan, without consideration. On March 29, 2022, the Board of Directors approved the grant of 1,153,500 options to 89 employees, three senior officers, one consultant, and five directors under the Company’s 2019 Equity Incentive Plan, without consideration.              
Exercise price     $ 1.41              
Vesting period     4 years              
Board of Directors [Member]                    
Stockholders Equity (Details) [Line Items]                    
Exercise price $ 0.66 $ 0.66                
Vesting period 4 years                  
Maruho Agreement [Member]                    
Stockholders Equity (Details) [Line Items]                    
Common stock shares issued         375,000          
Common stock per share         $ 8          
Total gross proceed         $ 3,000          
Grant date fair value         $ 1,024          
CFF Agreement [Member]                    
Stockholders Equity (Details) [Line Items]                    
Agreement type, description       the Company entered into a Securities Purchase Agreement with the Cystic Fibrosis Foundation (“CF Foundation”), an organization that historically played a role in supporting the development of innovative therapies for patients suffering from cystic fibrosis (“CF”). Under the terms of the agreement, the Company will receive up to $5,000 in two tranches. In the first tranche, which closed and fully received on December 21, 2021, the CF Foundation invested $3,000 as an initial equity investment based on a share price of $2.57. Upon completion of all patient dosing in Part 1 of the Company’s Phase 1b/2a study of BX004, the Company would have the right to receive the second tranche of $2,000, also as an equity investment. In the event that the average closing price of the Common Stock for the ten trading days prior to the second tranche completion is less than $2.57, the Company shall have the right in its sole discretion to waive the second tranche payment and in such event the CF Foundation shall not have any right to receive additional shares. The Company concluded that the second tranche is a freestanding financial instrument.